Dimitrios Mathios, MD

Dimitrios Mathios, MD

Assistant Professor of Neurosurgery

Director, Molecular Neuro-oncology Lab


  • Brain tumors 
  • Ependymomas 
  • Glioblastoma and other gliomas 
  • Hydrocephalus 
  • Intraventricular tumors 
  • Meningiomas

Call 314-362-3577 for Patient Appointments

My goal as a physician, surgeon, and scientist is to devise an individualized treatment plan for every patient I treat – not just focusing on prolonging their life, but providing them with a quality of life experience. Our team achieves this by listening to our patients, providing surgical excellence and collaborating with WashU experts to design the best steps forward.

Dr. Mathios


Athens College, Hellenic -American Educational Foundation
Athens, Greece
2000 – 2004

MD,  Kapodistrian University of Athens School of Medicine
Athens, Greece 
2004 – 2011 


Johns Hopkins University School of Medicine, Baltimore, Maryland
2015 – 2022 


Cancer Immunology, Genetics and Epigenetics
Johns Hopkins University School of Medicine, Baltimore, Maryland
2011 – 2015

Minimally Invasive Skull Base Surgery and Neuro-oncology
Weill Cornell Medicine,
New York Presbyterian, New York
2022 – 2023

Research focus

Brain tumors are devastating for the individuals affected and present a challenge for the doctors taking care of them. Despite the technological and surgical advancements, many patients succumb to their disease and others have serious side effects related to their treatments. With my expertise in Cancer Immunology, Genetics and Epigenetics, I have applied these tools towards the development of treatments before they become symptomatic, and at a point when they are easily resectable or curable with other treatments that could lead to improved outcomes. The Molecular Neuro-oncology lab is focused on developing genomic and epigenomic approaches for the development of liquid biopsy assays for non-invasive detection of brain tumors. The work performed is multidisciplinary and includes physicians, molecular biologists, and bioinformaticians.

View all research, publications and collaborations in Google Scholar

Honors & leadership roles

  • Grand Lodge of Greece Scholarship, 2004 – 2010 
  • Summa cum Laude, Kapodistrian University of Athens School of Medicine, 2011
  • Neurosurgery Residency Representative in the House Staff Council, The Johns Hopkins Hospital, 2019 – 2021
  • Harvey Cushing Hunterian Research Award, Johns Hopkins University School of Medicine,  2021 
  • Young Investigator Physician Scientist Research Award, Johns Hopkins University School of Medicine, 2022

Hospital appointments

Barnes-Jewish Hospital

Missouri Baptist Medical Center