Jon T. Willie, MD, PhD

Jon T. Willie, MD, PhD

Associate Professor of Neurosurgery, Biomedical Engineering, Psychiatry, Neuroscience and Neurology

Director of Stereotactic, Functional, and Epilepsy Neurosurgery

Castle Connolly Top Doctor


  • Brain cysts (arachnoid and colloid)
  • Chiari malformation
  • Epilepsy surgery
  • Minimally invasive and MRI-guided neurosurgery
  • Movement disorder surgery
  • Obstructive and communicating hydrocephalus
  • Psychiatric disorder surgery
  • Spasticity treatment

Call 314-362-3577 for Patient Appointments

Patient-oriented neuroscientific discovery, teaching, and surgical innovation are my passions.

Dr. Willie


BA, Biochemistry
The University of Texas
Austin, TX
1991– 1995 

PhD in Biomedical Sciences
The University of Texas Southwestern
Dallas, TX
1998– 2003 

MD, The University of Texas Southwestern Medical Center at Dallas
Dallas, TX
1996– 2005 


Department of Neurosurgery Washington University School of Medicine
St. Louis, MO
2005 – 2011


Fellowship, Clinical Stereotactic, Functional, and Epilepsy Neurosurgery
Emory University School of Medicine
Atlanta, GA
2011 – 2012  

Research Focus

Dr. Willie is a neurosurgeon-scientist with a robust clinical practice. He is funded by private foundations and the National Institute of Mental Health, and contributes high-profile clinical outcome publications, most notably on laser interstitial thermal therapy (minimally invasive laser ablation) for epilepsy.  He investigates deep brain stimulation to enhance learning and memory, and he is developing novel interventions to treat narcolepsy, hypersomnia, anxiety, brain injury, and post-traumatic stress disorder.

Willie Laboratory for Behavioral Neuromodulation

Willie Laboratory for Behavioral Neuromodulation

Focusing on characterizing the function of brain circuits that control memory and arousal in normal and disease states.

Honors & leadership roles

  • American Association of Neurological Surgeon/Congress of Neurological Surgeons Guidelines Committee.
  • Participate in generation and review of data-driven guidelines for clinical neurosurgical practice.
  • Reviewer, National Institute of Mental Health (NIMH), Learning and Memory (LAM) Study Section. 
  • “One in One Hundred” Mentor of the Year Award, Emory School of Medicine, Office of Postgraduate Education. 
  • Induction into “The Millipub Club”, Emory University School of Medicine, for having a publication with >1000 citations.  

Board certification

American Association of Neurological Surgeons, 2017 
American Board of Neurological Surgery, 2018 

Hospital appointments

Barnes-Jewish Hospital
Missouri Baptist Medical Center