Gregory J. Zipfel, MD

Gregory J. Zipfel, MD

Chair, Department of Neurosurgery

Ralph G. Dacey Distinguished Professor of Neurosurgery

Neurosurgeon-in-Chief, Barnes-Jewish Hospital

Castle Connolly Top Doctor


  • Acoustic neuromas
  • Brain tumors
  • Meningiomas
  • Pituitary tumors

Call 314-362-3577 for Patient Appointments

I strive to provide leading-edge surgical care to my patients, while also assuring that they and their families feel supported and individually cared for throughout.

Dr. Zipfel


BS, Biology, University of Illinois, Champaign
Urbana, Illinois

MD, Northwestern University Medical School
Chicago, Illinois


Resident, Neurological Surgery
University of Florida
Gainesville, Florida


Post-doctoral Research Fellow, Neurology
Washington University School of Medicine 
St. Louis, Missouri 

Cerebrovascular and Skull Base Surgery Fellow
Department of Neurological Surgery, University of Miami
Miami, Florida

Research focus

  1. Examine effects of amyloid-β on cerebral arteriole function and assessing its contribution to ischemic brain injury, cerebral amyloid angiopathy, and Alzheimer’s Disease.
  2. Explore mechanisms that underlie cerebral vasospasm and cognitive deficits following aneurysmal subarachnoid hemorrhage.

View research, publications and collaborations »

Zipfel Lab

Zipfel Lab

The Zipfel Lab aims to understand the mechanisms driving acute and chronic cerebrovascular diseases, identify new molecular targets, and develop novel therapies that will improve the lives of our patients.

Honors & leadership roles

  • Ralph G. Dacey Distinguished Endowed Professor of Neurological Surgery
  • Past Co-Chair, Editorial Board for Journal of Neurosurgery
  • Past Chair, Joint Cerebrovascular Section of the AANS/CNS
  • Board of Directors, Neurosurgery Research and Education Foundation
  • Vice-Chair of Research Committee, Neurosurgery Research and Education Foundation
  • Director, Emerging Investigator Mentoring Program of the American Academy of Neurological Surgery
  • Co-Director, NIH-funded National Neurosurgeon Research Career Development Program
  • Member, Advisory Council for Neurological Surgery for the American College of Surgeons
  • Member, STROKE Council / Scientific Statement Oversight Committee of the American Stroke Association
  • Member, Medical Advisory Board of the Brain Aneurysm Foundation
  • Standing Member, NIH Study Section (Neurological Sciences and Disorders-Clinical)

Board certification

Board certified, American Board of Neurological Surgery

Hospital appointments

Barnes-Jewish Hospital
St. Louis Children’s Hospital
Missouri Baptist Medical Center