Bhuvic Patel, MD

PGY6 Resident

MD Washington University
BS Brown University

Hometown: Westborough, MA

Research interests

I am currently completing a post-doctoral fellowship in the laboratory of Albert H.
Kim, MD, PhD
where I am pursuing three lines of basic science inquiry:

  • I am investigating the molecular biology of radiation resistant WHO grade II
    meningiomas using whole exome and RNA sequencing data, along with cell line
    models of meningioma. My overall goal is to identify predictive markers of treatment
    resistance, which may also serve as therapeutic targets that can be leveraged to
    sensitize grade II meningiomas to radiation.
  • I am classifying the vestibular schwannoma tumor microenvironment using single
    cell RNA and ATAC sequencing techniques and developing cell line models of
    vestibular schwannoma. My goal is to identify markers of tumor growth and radiation
    sensitivity in vestibular schwannomas.
  • Using an intracranial laser interstitial thermal therapy (LITT) mouse model developed
    in the lab, I am identifying the changes in the glioblastoma tumor microenvironment
    in response to LITT and performing pre-clinical trials of LITT in combination with
    adjuvant therapies. My goal is to understand the physiological responses to LITT to
    develop more effective combinatorial therapies for glioblastoma.
View research publications »

Grants

  • Neurosurgery Research and Education Foundation (NREF)
    Identifying biomarkers and mechanisms of radiation resistance in grade II meningiomas
    PI: Bhuvic Patel, MD
  • NIH R25 Research Training and Career Development Grant
    Identifying biomarkers and mechanisms of radiation resistance in grade II meningiomas
    PI: Gregory Zipfel, MD
  • Karen T. Romer Undergraduate Teaching and Research Assistantship Grant
    Transforming growth factor-beta1 causes pulmonary microvascular endothelial cell apoptosis via ALK5
    PI: Qing Lu, PhD

Honors & awards

  • Best Neurosurgery Resident Quality Improvement Project Award, 2020
  • Tae Sung Park, MD Neurosurgery Written Board Exam Highest Score Award, 2020
  • Tae Sung Park, MD Neurosurgery Written Board Exam Highest Score Award, 2019
  • Robert L. Grubb, Jr. MD Award for Clinical Excellence in Neurosurgery, 2018
  • Department of Neurosurgery Resident Teaching Award, 2018
  • Tae Sung Park, MD Neurosurgery Written Board Exam Highest Score Award, 2016
  • Washington University School of Medicine Class of 2015 Grand Marshall, 2015
  • Barnes-Jewish Hospital Medical Staff Association Full Tuition Medical School Scholarship, Washington University School of Medicine in St. Louis, 2011 – 2015