Anna Huguenard, MD

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I strive to combine my background in endovascular and open neurosurgical techniques with a research interest focused on improving patient outcomes with advanced neurotechnologies to provide the most cutting-edge care and hope for all of my patients.

– Dr. Huguenard

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Research focus

I am fundamentally interested in how we can optimize patient recovery following neurovascular or traumatic brain injury. To better understand the cascade of secondary injury and neuroinflammation following initial injury, we are expanding our efforts to collect and analyze patient samples over time allowing us to best identify targets for intervention. We have also developed a highly collaborative community across the specialties of Neurosurgery, Neurology, and Engineering to develop new technologies and develop cutting edge therapies to apply in the post-injury time period. Currently, we are harnessing the power of neuromodulation via non-invasive vagus nerve stimulation to reduce inflammation and improve outcomes by implementing ongoing clinical trials in several key diseases: subarachnoid hemorrhage, intraparenchymal hemorrhage, and acute ischemic stroke. 

I also have a particular clinical interest in the neurovascular manifestations of connective tissue diseases (i.e. Loeys-Dietz Syndrome, vascular Ehlers Danlos, and Marfan’s), and the management of patients with these diseases.

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Honors & leadership roles

• AANS Natus Fellow/Resident Neurocritical Care Award, 2025
• Neurocritical Care Society, Best Scientific Abstract Award, 2024
• Society of NeuroInterventional Surgery Annual Meeting Fellow Abstract Award, 2023
• Society of NeuroInterventional Surgery Annual Meeting Travel Grant, 2023
• American Academy of Neurological Surgeons Resident Runner Up Award, 2023
• International Symposium on Marfan Science in Paris Travel Award
• Annual Award for Outstanding Clinical Research by a Resident in Neurological Surgery, Washington University School of Medicine, 2021, 2022, & 2023
• Awarded the Venna D. Mummaneni NREF WINS resident award at the American Association of Neurological Surgeons (AANS) Meeting, 2022
• Awarded the Louise Eisenhardt Travel Scholarship at the American Association of Neurological Surgeons (AANS) Meeting, 2022
• Awarded top Basic Science Poster in the Functional Section by the Congress of Neurological Surgeons (CNS), 2021
• The Robert L. Grubb Jr., MD Clinical Excellence Award, 2019
• Alpha Omega Alpha Honor Medical Society, Emory University, 2015
• Phi Beta Kappa, Indiana University, 2010
• Cox Research Scholar Program – full expense scholarship, Indiana University, 2007-2011

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Hospital appointments

Barnes-Jewish Hospital

Barnes-Jewish St. Peters Hospital

Missouri Baptist Medical Center

St. Louis Children’s Hospital